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学校検尿での尿糖陽性精査で判明したバセドウ病に伴う耐糖能異常の小児例
https://uoeh-u.repo.nii.ac.jp/records/808
https://uoeh-u.repo.nii.ac.jp/records/80868aa3eed-53e6-48a7-a333-9806ac6b53ae
名前 / ファイル | ライセンス | アクション |
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S00040303.pdf (594.5 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-12-31 | |||||
タイトル | ||||||
タイトル | 学校検尿での尿糖陽性精査で判明したバセドウ病に伴う耐糖能異常の小児例 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | A Pediatric Case of Graves’ Hyperthyroidism with Associated Glucose Intolerance Detected by a Urine Glucose Screening Program at School | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | バセドウ病 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 甲状腺機能亢進症 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 糖尿病 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 学校検尿 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 耐糖能異常 | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Graves’ disease | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | hyperthyroidism | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | glycosuria | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | urine glucose screening program | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | glucose intolerance | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
記事区分 | ||||||
値 | Case Report(s) | |||||
著者 |
池上, 朋未
× 池上, 朋未× 山本, 幸代× 後藤, 元秀× 川越, 倫子× 河田, 泰定× 楠原, 浩一× Ikegami, Tomomi× Yamamoto, Yukiyo× Goto, Motohide× Kawagoe, Rinko× Kawada, Yasusada× Kusuhara, Koichi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We report here a 13-year-old female with Graves’ disease, whose diagnostic clue was glycosuria, which was detected by a urine glucose screening program at school. She had had mild general malaise, and a physical examination revealed a slightly enlarged thyroid gland. Hyperthyroidism (thyroid-stimulating hormone (TSH) < 0.01 μU/ml, free triiodothyronine (fT3) 23.57 pg/ml, free thyroxine (fT4) 3.38 ng/dl) and anti-thyroid autoantibodies (TRAb 43.6%) were detected in laboratory tests, and her plasma glucose at 120 minutes was 142 mg/dl in a 75 g oral glucose tolerance test. She was diagnosed as having borderline diabetes. These findings revealed a diagnosis of Graves’ hyperthyroidism with associated impaired glucose tolerance. Although it is reported that many adults with hyperthyroidism develop disorders of glucose metabolism, pediatric patients rarely have complications of glucose intolerance or diabetes mellitus, and there are no previous reports of Graves’ disease diagnosed by a urine glucose screening program at school. This case suggests a possibility of abnormalities in glucose metabolism even in pediatric cases of Graves’ disease. To avoid overlooking the diagnosis of glucose intolerance associated with hyperthyroidism, a careful medical interview and examination should be performed even if the clinical features are mild. | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 学校検尿での尿糖陽性を契機に,バセドウ病による甲状腺機能亢進症,およびそれに伴う耐糖能異常と診断した小児例を報告する.症例は13歳女児.学校検尿で尿糖陽性が判明した.多飲や多尿の自覚はなかった.受診時,倦怠感,甲状腺腫が認められ,甲状腺機能亢進(TSH < 0.01 μU/ml,fT3 23.57 pg/ml,fT4 3.38 ng/dl),自己抗体陽性(TRAb 43.6%)で,バセドウ病と診断した.経口ブドウ糖負荷試験(OGTT)では負荷後120分血糖のみが高値(142 mg/dl)で境界型であった.成人では甲状腺機能亢進症に耐糖能異常を発症することが報告されている.小児では耐糖能異常や糖尿病を合併した報告は稀で,学校検尿での尿糖陽性を契機にバセドウ病が判明した例はない.甲状腺機能亢進症に伴う耐糖能異常を見逃さないために,臨床症状が軽微であっても慎重な問診と診察を行う必要がある. | |||||
書誌情報 |
産業医科大学雑誌 en : Journal of UOEH 巻 40, 号 3, p. 231-236, 発行日 2018-09-01 |
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出版者 | ||||||
出版者 | 産業医科大学(産業医科大学学会) | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | ISSN 0387-821X(PRINT), ISSN 2187-2864(ONLINE) | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://www.jstage.jst.go.jp/browse/juoeh/40/3/_contents/-char/ja | |||||
関連名称 | Journal of UOEH | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://www.uoeh-u.ac.jp/kouza/journal/i_2018-3j.html | |||||
関連名称 | 産業医科大学雑誌 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |