{"created":"2023-06-20T15:46:22.357237+00:00","id":975,"links":{},"metadata":{"_buckets":{"deposit":"c1e84f6e-9680-40a7-ae92-fab0faef10c4"},"_deposit":{"created_by":4,"id":"975","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"975"},"status":"published"},"_oai":{"id":"oai:uoeh-u.repo.nii.ac.jp:00000975","sets":["13:14:52"]},"author_link":["4820","4831","4818","4825","4826","4829","4815","4819","4833","4830","4814","4816","4823","4813","4828","4832","4822","4827","4817","4812","4824","4821"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-12-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"330","bibliographicPageStart":"323","bibliographicVolumeNumber":"44","bibliographic_titles":[{"bibliographic_title":"産業医科大学雑誌"},{"bibliographic_title":"Journal of UOEH","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We aimed to clarify the effect of aging on trabecular bone volume and trabecular bone microstructure in a rat model of Duchenne muscular dystrophy (DMD). Six rats each of wild type (WT) and DMD model at 15 weeks of age, and 4 rats each at 30 weeks of age, were analyzed by dual energy X-ray absorptiometry and by micro-CT for analysis of trabecular and cortical bone of the femur. Bone mineral density was significantly lower in the DMD group than in the WT group at both 15 and 30 weeks of age. Micro-CT showed that trabecular bone volume and number were not significantly different between the two groups at 15 weeks, but at 30 weeks both were significantly lower in the DMD group than in the WT group. Connectivity density and structure model index were not significantly different between the two groups at 15 weeks, but at 30 weeks they differed significantly. No significant differences between the WT and DMD groups in cortical thickness and cortical area were evident at both 15 and 30 weeks. In conclusion, trabecular bone volume is significantly reduced, with deteriorated microstructure, with aging in a rat model of DMD.","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"産業医科大学　（産業医科大学学会）"}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Journal of UOEH"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.uoeh-u.ac.jp/kouza/journal/intro_e.html","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"産業医科大学雑誌"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.uoeh-u.ac.jp/kouza/journal/intro_j.html","subitem_relation_type_select":"URI"}}]},"item_10001_select_24":{"attribute_name":"記事区分","attribute_value_mlt":[{"subitem_select_item":"Original"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"ISSN 0387-821X（PRINT）, ISSN 2187-2864(ONLINE)","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"小原, 日奈子"},{"creatorName":"オバラ, ヒナコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"4812","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田島, 貴文"},{"creatorName":"タジマ, タカフミ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"4813","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"塚本, 学"},{"creatorName":"ツカモト, マナブ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"4814","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"山中, 芳亮"},{"creatorName":"ヤマナカ, ヨシアキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"4815","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鈴木, 仁士"},{"creatorName":"スズキ, ヒトシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"4816","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"善家, 雄吉"},{"creatorName":"ゼンケ, ユウキチ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"4817","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"川崎, 展"},{"creatorName":"カワサキ, マコト","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"4818","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鴻崎, 香里奈"},{"creatorName":"コウザキ, カリナ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"4819","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中里, 浩一"},{"creatorName":"ナカザト, コウイチ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"4820","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"平沼, 憲治"},{"creatorName":"ヒラヌマ, ケンジ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"4821","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"酒井, 昭典"},{"creatorName":"サカイ, アキノリ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"4822","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Obara, Hinako","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4823","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tajima, Takafumi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4824","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsukamoto, Manabu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4825","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamanaka, Yoshiaki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4826","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suzuki, Hitoshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4827","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Zenke, Yukichi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4828","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kawasaki, Makoto","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4829","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kouzaki, Karina","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4830","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nakazato, Koichi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4831","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hiranuma, Kenji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4832","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sakai, Akinori","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4833","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-01-05"}],"displaytype":"detail","filename":"01-小原 日奈子.pdf","filesize":[{"value":"1.9 MB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"S00044401","url":"https://uoeh-u.repo.nii.ac.jp/record/975/files/01-小原 日奈子.pdf"},"version_id":"4c7ffb37-9553-46bf-ab62-8c6bd4cff65d"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"デュシェンヌ型筋ジストロフィー","subitem_subject_scheme":"Other"},{"subitem_subject":"骨密度","subitem_subject_scheme":"Other"},{"subitem_subject":"海綿骨","subitem_subject_scheme":"Other"},{"subitem_subject":"皮質骨","subitem_subject_scheme":"Other"},{"subitem_subject":"ラットモデル","subitem_subject_scheme":"Other"},{"subitem_subject":"Duchenne muscular dystrophy","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"bone mineral density","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"trabecular bone","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"cortical bone","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"rat model","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"デュシェンヌ型筋ジストロフィーのラットモデルにおいて海綿骨量は加齢とともに微小構造の劣化を伴って減少する","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"デュシェンヌ型筋ジストロフィーのラットモデルにおいて海綿骨量は加齢とともに微小構造の劣化を伴って減少する"},{"subitem_title":"Trabecular Bone Volume Is Reduced, With Deteriorated Microstructure, With Aging in a Rat Model of Duchenne Muscular Dystrophy","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"4","path":["52"],"pubdate":{"attribute_name":"公開日","attribute_value":"2023-04-01"},"publish_date":"2023-04-01","publish_status":"0","recid":"975","relation_version_is_last":true,"title":["デュシェンヌ型筋ジストロフィーのラットモデルにおいて海綿骨量は加齢とともに微小構造の劣化を伴って減少する"],"weko_creator_id":"4","weko_shared_id":-1},"updated":"2023-06-20T15:51:44.191652+00:00"}