{"created":"2023-06-20T15:46:17.786891+00:00","id":890,"links":{},"metadata":{"_buckets":{"deposit":"e472f05b-9814-4111-bc28-300302d094ab"},"_deposit":{"created_by":4,"id":"890","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"890"},"status":"published"},"_oai":{"id":"oai:uoeh-u.repo.nii.ac.jp:00000890","sets":["13:20:51"]},"author_link":["4119","4118"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-03-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"31","bibliographicPageStart":"25","bibliographicVolumeNumber":"43","bibliographic_titles":[{"bibliographic_title":"産業医科大学雑誌"},{"bibliographic_title":"Journal of UOEH","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"In the event of a high-dose radiation exposure accident, adipose-derived stem cell (ADSC) transplantation might be used as an emergency medical treatment to compensate for bone marrow failure. To investigate the possible course of that treatment, we examined whether transplantation of ADSCs into whole-body X-ray irradiated mice would provide resistance to radiation damage. ADSCs were obtained from a primary culture of adipocytes from adipose tissue of syngeneic mice. The ADSCs were transplanted via an intravenous (i.v.) route after whole-body irradiation (6 Gy, X-rays) of the ICR mice. Fifty days after transplantation, the survival rate of the transplanted group was 40% higher than the control group, and the difference in survival rates was maintained in the following 200 days. After 400 days, however, the difference in survival rates became smaller and disappeared after 650 days. The results indicate that ADSC transplantation may reduce lethality from acute radiation bone marrow injury for several hundred days.\n","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"産業医科大学　（産業医科大学学会）"}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Journal of UOEH"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.uoeh-u.ac.jp/kouza/journal/intro_e.html","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"産業医科大学雑誌"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.uoeh-u.ac.jp/kouza/journal/intro_j.html","subitem_relation_type_select":"URI"}}]},"item_10001_select_24":{"attribute_name":"記事区分","attribute_value_mlt":[{"subitem_select_item":"Original"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"ISSN 0387-821X（PRINT）, ISSN 2187-2864(ONLINE)","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"大津山, 彰 "},{"creatorName":"オオツヤマ, アキラ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"4118","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ootsuyama, Akira ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4119","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-04-05"}],"displaytype":"detail","filename":"03-大津山 彰.pdf","filesize":[{"value":"565.0 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"S00043103","url":"https://uoeh-u.repo.nii.ac.jp/record/890/files/03-大津山 彰.pdf"},"version_id":"52d972e8-3190-45d6-b126-dc4dc4d8ef3d"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"脂肪由来幹細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"放射線障害","subitem_subject_scheme":"Other"},{"subitem_subject":"移植","subitem_subject_scheme":"Other"},{"subitem_subject":"生存","subitem_subject_scheme":"Other"},{"subitem_subject":"adipose-derived stem cell","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"radiation injury","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"transplantation, survival","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"放射線被ばくマウスへのADSC移植による寿命延長効果","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"放射線被ばくマウスへのADSC移植による寿命延長効果"},{"subitem_title":"Life-Prolonging Effects of Adipose Tissue-Derived Stem Cell Transplantation into Mice Exposed to a Lethal Dose of X-Rays","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"4","path":["51"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-04-05"},"publish_date":"2021-04-05","publish_status":"0","recid":"890","relation_version_is_last":true,"title":["放射線被ばくマウスへのADSC移植による寿命延長効果"],"weko_creator_id":"4","weko_shared_id":-1},"updated":"2023-06-20T15:53:59.432664+00:00"}