{"created":"2023-06-20T15:46:15.505753+00:00","id":848,"links":{},"metadata":{"_buckets":{"deposit":"906fe598-7de3-41e3-ae17-c7dd13e56551"},"_deposit":{"created_by":4,"id":"848","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"848"},"status":"published"},"_oai":{"id":"oai:uoeh-u.repo.nii.ac.jp:00000848","sets":["13:22:41"]},"author_link":["3592","3596","3599","3601","3587","3590","3586","3597","3585","3589","3595","3598","3594","3600","3584","3591","3593","3588"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-09-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"302","bibliographicPageStart":"295","bibliographicVolumeNumber":"41","bibliographic_titles":[{"bibliographic_title":" 産業医科大学雑誌"},{"bibliographic_title":"Journal of UOEH","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"This study aimed to estimate the incidence and prognosis of neonatal disseminated intravascular coagulation (DIC) in Japan by analyzing data retrieved from a national administrative database. Clinically, the prognosis of DIC in neonates is poor, but there is little epidemiological data in Japan. This retrospective observational study identified patients diagnosed with neonatal DIC and who were registered in the Japanese diagnosis procedure combination (DPC) database between April 1, 2014 and March 31, 2016. The patients, who were diagnosed with neonatal DIC, included those with ICD-10 code D65 or P60 in primary and secondary diagnosis, with comorbid conditions existing at admission, and with complications occurring after admission. Of 78,073 neonates admitted to 1,474 neonatal intensive care units, 1,864 (2.4%) were diagnosed with DIC. There was no difference between sexes in incidence of DIC; the incidence of DIC was higher in extremely low birth weight infants (9.8%), and significantly higher than that in normal birth weight infants. The overall mean length of hospital stay was longer in neonates with DIC (69.5 days) than in those without DIC (32.6 days, P < 0.001). The number of deaths was 1,156 (1.5%). In-hospital mortality was significantly higher in neonates with DIC (14.1%) than in those without DIC (1.2%, P < 0.001), especially in premature babies. This nationwide study was the first report to investigate the incidence and in-hospital mortality of neonatal DIC in Japan. Neonatal DIC has a significant impact on prognosis, and its influence is greater in premature than in term infants.\n","subitem_description_type":"Abstract"},{"subitem_description":"日本における新生児播種性血管内凝固症候群（disseminated intravascular coagulation: DIC）の発生率は不明であり，今回われわれは診断群分類（diagnosis procedure combination: DPC）データを用いてわが国における新生児DICについての疫学研究を行った． 診断群分類研究機構にデータが提出されている1,474施設に2014年4月1日から2016年3月31日の間に入院し，入院時年齢が0歳かつ新生児特定集中治療室管理料を算定している児を対象とした．「主傷病名」，「入院の契機となった傷病名」，「最も医療資源を消費した傷病名」，「2番目に医療資源を消費した傷病名」，「入院時併存症」，「入院後発症病名」のいずれかにinternational classification of disease（ICD）-10上で播種性血管内凝固（D65），新生児播種性血管内凝固（P60）が登録されている症例を抽出した．78,073例が対象となり，新生児DICの発生数は1,864例，発生率は2.4%であった．男女差は認めなかった．出生体重別では1,000 g未満では9.8%と有意に高く，在胎期間別の検討で28週未満では10.2%がDICを発症していた．DICを発生した症例の平均在院日数は69.5日とDICを発症しなかった症例の32.6日と比較して有意に延長していた．全死亡数は1,156 例（1.5%），DIC発症群では262例/1,864 例（14.1%）で，DIC非発症群の894例/76,209 例（1.2%）に比較して有意に院内死亡率が高かった．本研究はDPCデータを用いたわが国における初めての新生児DICについての大規模疫学研究報告である．新生児DICの発症は予後と強く関連し，より未熟な児ほど大きな影響を受ける．\n","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"産業医科大学（産業医科大学学会）"}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Journal of UOEH　"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.jstage.jst.go.jp/browse/juoeh/41/3/_contents/-char/ja","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"産業医科大学雑誌　"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.uoeh-u.ac.jp/kouza/journal/i_2019-3j.html","subitem_relation_type_select":"URI"}}]},"item_10001_select_24":{"attribute_name":"記事区分","attribute_value_mlt":[{"subitem_select_item":"Original"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"ISSN 0387-821X(PRINT), ISSN 2187-2864(ONLINE)","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"荒木, 俊介"}],"nameIdentifiers":[{"nameIdentifier":"3584","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"冨岡, 慎一"}],"nameIdentifiers":[{"nameIdentifier":"3585","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"大谷, 誠"}],"nameIdentifiers":[{"nameIdentifier":"3586","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"菅, 秀太郎"}],"nameIdentifiers":[{"nameIdentifier":"3587","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"市川, 俊"}],"nameIdentifiers":[{"nameIdentifier":"3588","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"松田, 晋哉"}],"nameIdentifiers":[{"nameIdentifier":"3589","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"伏見, 清秀"}],"nameIdentifiers":[{"nameIdentifier":"3590","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"楠原, 浩一"}],"nameIdentifiers":[{"nameIdentifier":"3591","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"白幡, 聡"}],"nameIdentifiers":[{"nameIdentifier":"3592","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Araki, Shunsuke","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3593","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tomioka, Shinichi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3594","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Otani, Makoto ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3595","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suga, Shutaro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3596","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ichikawa, Shun","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3597","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Matsuda, Shinya ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3598","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fushimi, Kiyohide","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3599","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kusuhara, Koichi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3600","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shirahata, Akira","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3601","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-12-18"}],"displaytype":"detail","filename":"S00041304.pdf","filesize":[{"value":"500.5 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"S00041304.pdf","url":"https://uoeh-u.repo.nii.ac.jp/record/848/files/S00041304.pdf"},"version_id":"d07e1d21-5d5e-4805-9171-f8e48f52d721"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"院内死亡率","subitem_subject_scheme":"Other"},{"subitem_subject":"在院日数","subitem_subject_scheme":"Other"},{"subitem_subject":"罹患率","subitem_subject_scheme":"Other"},{"subitem_subject":"新生児","subitem_subject_scheme":"Other"},{"subitem_subject":"DIC","subitem_subject_scheme":"Other"},{"subitem_subject":"in-hospital mortality","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"length of hospital stay","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"morbidity rate","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"neonates","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"DIC","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"DPCデータを用いた日本における新生児DICの発生と院内死亡率","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"DPCデータを用いた日本における新生児DICの発生と院内死亡率"},{"subitem_title":"Incidence and In-Hospital Mortality of Neonatal Disseminated Intravascular Coagulation in Japan: An Observational Study of a Nationwide Hospital Claims Database","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"4","path":["41"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-12-18"},"publish_date":"2019-12-18","publish_status":"0","recid":"848","relation_version_is_last":true,"title":["DPCデータを用いた日本における新生児DICの発生と院内死亡率"],"weko_creator_id":"4","weko_shared_id":-1},"updated":"2023-06-20T15:55:18.860386+00:00"}