{"created":"2023-06-20T15:46:12.481098+00:00","id":799,"links":{},"metadata":{"_buckets":{"deposit":"e2657f79-1a8d-416a-9d1c-09249c1f57c8"},"_deposit":{"created_by":4,"id":"799","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"799"},"status":"published"},"_oai":{"id":"oai:uoeh-u.repo.nii.ac.jp:00000799","sets":["13:17:39"]},"author_link":["3024","3025","3028","3023","3021","3022","3029","3034","3020","3035","3036","3027","3033","3032","3026","3037","3030","3031"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-06-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"145","bibliographicPageStart":"139","bibliographicVolumeNumber":"40","bibliographic_titles":[{"bibliographic_title":"産業医科大学雑誌"},{"bibliographic_title":"Journal of UOEH","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"A post-marketing surveillance study reported fatalities following tissue plasminogen activator administration in acute aortic dissection (AAD) with the symptoms of acute ischemic stroke (AIS) patients. Therefore, it is important to discriminate AAD from AIS. The present study aimed to investigate whether fibrinogen/fibrin degradation products (FDP) value can be useful in differential diagnosis between AAD and AIS. The study group comprised 20 AAD patients (10 men and 10 women; age 63.9 ± 13.6 years) and 159 AIS patients (91 men and 68 women; age 74.2±10.6 years) who were transported to our hospital from 2007 to 2012. The AAD cases were further divided into patent-type AAD and thrombosed-type AAD. FDP values were significantly higher in the AAD group than in the AIS group (18.15 [5.2–249.9] μg/ml vs. 2.3 [1.5–4.45] μg/ml; P<0.001). In AAD groups, FDP values were significantly higher in the patent-type AAD group (n = 9) than in the thrombosed type AAD group (n = 11) (293.2 μg/ml [63.1–419.6 μg/ml] vs. 5.6 μg/ml [3.8–7.9 μg/ml]. FDP values were significantly higher in patients with AAD than in those with AIS, especially those with patent-type AAD compared with AIS patients. High FDP values may be a useful marker for differential diagnosis between patent-type AAD and AIS.","subitem_description_type":"Abstract"},{"subitem_description":"急性虚血性脳卒中の症状を有する急性大動脈解離症例に組織プラスミノーゲンアクチベータ（tissue plasminogen activator）を使用し，死亡に至った事例が報告されている．それゆえ急性大動脈解離と急性虚血性脳卒中の鑑別が重要である．本研究ではフィブリノゲン/ フィブリン分解産物（FDP）値が急性大動脈解離と急性虚血性脳卒中の鑑別に有用であるかを調査した．研究対象者は，2007年から2012年に当院へ搬送された，20名の急性大動脈解離症例（男性10名，女性10名，平均年齢63.9±13.6歳）および159名の急性虚血性脳卒中症例（男性91名，女性68名，平均年齢74.2± 10.6歳）であった．さらに大動脈解離症例を偽腔開存型急性大動脈解離群と血栓閉塞型大動脈解離群に分類した．FDP値は急性虚血性脳卒中群と比較し急性大動脈解離群で有意に高くなっていた（18.15［ 5.2–249.9］μg/ml vs. 2.3［ 1.5–4.45］ μg/ml，P<0.001）．急性大動脈解離症例において，血栓閉塞型大動脈解離群（n=11）と比較して，偽腔開存型大動脈解離群（n=9）で有意にFDP値が高くなっていた（293.2 μg/ml［ 63.1–419.6 μg/ml］ vs. 5.6 μg/m［3.8–7.9 μg/ml］．結論として，急性虚血性脳卒中群と比較し急性大動脈解離群，特に急性虚血性脳卒中と比較し，偽腔開存型大動脈解離群でFDP値が有意に高くなっている．FDP値の上昇は急性虚血性脳卒中と偽腔開存型急性大動脈解離の鑑別に有用なマーカーとなる可能性がある．","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"産業医科大学（産業医科大学学会）"}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Journal of UOEH"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.jstage.jst.go.jp/browse/juoeh/40/2/_contents/-char/ja","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"産業医科大学雑誌"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.uoeh-u.ac.jp/kouza/journal/i_2018-2j.html","subitem_relation_type_select":"URI"}}]},"item_10001_select_24":{"attribute_name":"記事区分","attribute_value_mlt":[{"subitem_select_item":"Original"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"ISSN 0387-821X(PRINT), ISSN 2187-2864(ONLINE)","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"二瓶, 俊一"}],"nameIdentifiers":[{"nameIdentifier":"3020","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"荒井, 秀明"}],"nameIdentifiers":[{"nameIdentifier":"3021","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"内田, 貴之"}],"nameIdentifiers":[{"nameIdentifier":"3022","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"金澤, 綾子"}],"nameIdentifiers":[{"nameIdentifier":"3023","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"遠藤, 武尊"}],"nameIdentifiers":[{"nameIdentifier":"3024","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"尾辻, 健"}],"nameIdentifiers":[{"nameIdentifier":"3025","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"原山, 信也"}],"nameIdentifiers":[{"nameIdentifier":"3026","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"相原, 啓二"}],"nameIdentifiers":[{"nameIdentifier":"3027","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"蒲地, 正幸"}],"nameIdentifiers":[{"nameIdentifier":"3028","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nihei, Shun-ichi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3029","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Arai, Hideaki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3030","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Uchida, Takayuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3031","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kanazawa, Ayako","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3032","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Endo, Takeru","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3033","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Otsuji, Ken","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3034","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Harayama, Nobuya","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3035","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Aibara, Keiji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3036","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kamochi, Masayuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"3037","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-03-18"}],"displaytype":"detail","filename":"S00040201.pdf","filesize":[{"value":"824.3 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"S00040201.pdf","url":"https://uoeh-u.repo.nii.ac.jp/record/799/files/S00040201.pdf"},"version_id":"4bccc08d-251a-42db-93e9-49724311a7c1"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"急性大動脈解離","subitem_subject_scheme":"Other"},{"subitem_subject":"急性虚血性脳卒中","subitem_subject_scheme":"Other"},{"subitem_subject":"フィブリノゲン/ フィブリン分解産物","subitem_subject_scheme":"Other"},{"subitem_subject":"acute aortic dissection","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"acute ischemic stroke","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"fibrinogen/fibrin degradation products","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"急性虚血性脳卒中と急性大動脈解離の鑑別診断におけるフィブリノゲン/フィブリン分解産物の有用性","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"急性虚血性脳卒中と急性大動脈解離の鑑別診断におけるフィブリノゲン/フィブリン分解産物の有用性"},{"subitem_title":"Usefulness of Fibrinogen/Fibrin Degradation Products Value in Differential Diagnosis Between Acute Ischemic Stroke and Acute Aortic Dissection","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"4","path":["39"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-08-03"},"publish_date":"2020-08-03","publish_status":"0","recid":"799","relation_version_is_last":true,"title":["急性虚血性脳卒中と急性大動脈解離の鑑別診断におけるフィブリノゲン/フィブリン分解産物の有用性"],"weko_creator_id":"4","weko_shared_id":-1},"updated":"2023-06-20T15:56:43.624348+00:00"}