{"created":"2023-06-20T15:46:11.223754+00:00","id":776,"links":{},"metadata":{"_buckets":{"deposit":"5ea753a6-be13-4519-adf1-be8d51ab4f78"},"_deposit":{"created_by":4,"id":"776","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"776"},"status":"published"},"_oai":{"id":"oai:uoeh-u.repo.nii.ac.jp:00000776","sets":["13:23:35"]},"author_link":["2788","2786","2790","2791","2789","2787"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-09-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"199","bibliographicPageStart":"187","bibliographicVolumeNumber":"39","bibliographic_titles":[{"bibliographic_title":"産業医科大学雑誌"},{"bibliographic_title":"Journal of UOEH","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Many kinds of manufactured nanomaterials (MNMs) have been developed and used as basic materials of industrial products, and they may pose health risks for workers in not only developed countries but also in developing countries.  Few studies have looked at the evidence for effects of controls that mitigate the risk of exposure to MNMs.  Therefore, we systematically searched the literature from the year 2000 to 2015.  We included studies that compared the use of an exposure control to the situation without such a technique and those that measured the exposure to MNMs as the outcome.  In order to evaluate the effectiveness of these controls, we used their “protection factor”, defined as the ratio between concentrations without and with the control.  We located 1,131 references in PubMed and other lists, and out of these references, 41 studies fulfilled our inclusion criteria.  We categorized them as engineering controls such as enclosure, local exhaust ventilation or process automation, and as personal protective equipment (PPE).  For enclosure systems we found a protection factor beyond 100.  For other engineering controls, the better controls scored 10 to 20, but many cases of local exhaust ventilation had a protection factor of less than 10 and some cases even increased exposure.  PPE such as N95 or equivalent filtering respirators had a protection factor of approximately 10 tested with nano-sized aerosols.  We conclude that there is low quality evidence that specific engineering controls can reduce exposure to MNMs but that enclosure is considerably more effective.  For respiratory protection the evidence is of very low quality due to the lack of field studies.  This information can be used to decide about controls when exposure to MNMs exceeds proposed occupational exposure limits or when no toxicological information is available for a MNM.","subitem_description_type":"Abstract"},{"subitem_description":"多くの工業用ナノマテリアルが産業製品の基本材料として開発され使用されており，それらは開発国 だけでなく開発途上国の労働者への健康リスクを持つ可能性がある．工業用ナノマテリアルの曝露低減対策の効果 を証明する研究はほとんどないので，我々は2000年から2015年までに公表され特定された工業用ナノマテリアルの リスク低減対策の研究をシステマティックに調査した．ここでは，状況に曝露低減対策を入れた場合と入れない場 合を比較し，工業用ナノマテリアルの曝露を測定した研究を採用した．これらの対策の効果を判定するために，我々 は工業用ナノマテリアルの低減対策の効果の尺度として防護係数，対策の有無による有害物濃度の比として定義さ れる文献を使用した．ここではPubMedの1,131レコードや他の文献リストから， 41の文献を条件に合致したものと して抽出した．そして局所排気装置，密閉化，プロセス自動化などの工学的対策や，個人用保護具に分類した．密閉 化の対策では，防護係数が100を超える場合があった．他の工学的対策では，よい結果では防護係数は10から20で あったが，多くの局所排気装置では10以下，時に状況を悪くする場合もあった．N95や同等のグレードの使い捨て式 防じんマスクはナノサイズの試験エアロゾルに対して10程度の防護係数を持っていた．工学的対策は工業用ナノ マテリアルへの曝露を低減するが，密閉化のシステムの方がより効果的であることに弱い証拠があると結論付けた． 呼吸用保護具は現場での研究が少ないため弱い証拠があると判定した．工業用ナノマテリアルが職業曝露限界を超 える場合， または， その毒性情報がない場合に対策を決定するため上記の情報を使うことができる．","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"産業医科大学（産業医科大学学会）"}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Journal of UOEH"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.jstage.jst.go.jp/browse/juoeh/39/3/_contents/-char/ja","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"産業医科大学雑誌"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.uoeh-u.ac.jp/kouza/journal/i_2017-3j.html","subitem_relation_type_select":"URI"}}]},"item_10001_select_24":{"attribute_name":"記事区分","attribute_value_mlt":[{"subitem_select_item":"Review"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"ISSN 0387-821X(PRINT), ISSN 2187-2864(ONLINE)","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"明星, 敏彦"}],"nameIdentifiers":[{"nameIdentifier":"2786","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"永田, 智久"}],"nameIdentifiers":[{"nameIdentifier":"2787","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"ジョス, バビーク"}],"nameIdentifiers":[{"nameIdentifier":"2788","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Myojo, Toshihiko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2789","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nagata, Tomohisa","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2790","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Jos, Verbeek","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2791","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-03-18"}],"displaytype":"detail","filename":"S00039301.pdf","filesize":[{"value":"1.4 MB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"S00039301.pdf","url":"https://uoeh-u.repo.nii.ac.jp/record/776/files/S00039301.pdf"},"version_id":"db055e0c-d543-47ac-aabc-6fca5d2cb57a"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"工業用ナノマテリアル","subitem_subject_scheme":"Other"},{"subitem_subject":"システマティックレビュー","subitem_subject_scheme":"Other"},{"subitem_subject":"工学的対策","subitem_subject_scheme":"Other"},{"subitem_subject":"呼吸用保護具","subitem_subject_scheme":"Other"},{"subitem_subject":"プロセス自動化","subitem_subject_scheme":"Other"},{"subitem_subject":"manufactured nanomaterials","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"systematic review","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"engineering control","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"respirator","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"process automation","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"工業用ナノマテリアルの製造と取扱いで用いられる個別のリスク低減対策の効果：システマティック レビュー","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"工業用ナノマテリアルの製造と取扱いで用いられる個別のリスク低減対策の効果：システマティック レビュー"},{"subitem_title":"The Effectiveness of Specific Risk Mitigation Techniques Used in the Production and Handling of Manufactured Nanomaterials: A Systematic Review","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"4","path":["35"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-08-03"},"publish_date":"2020-08-03","publish_status":"0","recid":"776","relation_version_is_last":true,"title":["工業用ナノマテリアルの製造と取扱いで用いられる個別のリスク低減対策の効果：システマティック レビュー"],"weko_creator_id":"4","weko_shared_id":-1},"updated":"2023-06-20T15:57:36.031019+00:00"}