{"created":"2023-06-20T15:46:08.608104+00:00","id":732,"links":{},"metadata":{"_buckets":{"deposit":"1e879b32-9559-416a-8b1b-8a18378514bf"},"_deposit":{"created_by":4,"id":"732","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"732"},"status":"published"},"_oai":{"id":"oai:uoeh-u.repo.nii.ac.jp:00000732","sets":["13:24:33"]},"author_link":["2301","2318","2306","2324","2321","2300","2323","2332","2305","2303","2312","2304","2295","2328","2333","2302","2322","2327","2310","2296","2319","2320","2314","2316","2308","2294","2311","2330","2325","2309","2317","2298","2315","2329","2313","2297","2307","2299","2326","2331"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-03-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"23","bibliographicPageStart":"17","bibliographicVolumeNumber":"38","bibliographic_titles":[{"bibliographic_title":"産業医科大学雑誌"},{"bibliographic_title":"Journal of UOEH","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"近年，末梢肺病変の診断率改善のためにガイドシース併用気管支腔内超音波断層法（endobronchial ultrasonography with a guide sheath（EBUS-GS））は汎用される手技となっている．本研究ではEBUS-GSを用いた末梢型肺癌の診断関連因子を後ろ向きに検討した．2014年8月から2015年9月に産業医科大学病院呼吸器内科でEBUSGSを行い，最終的に原発性肺癌と診断した症例（76例）を対象とした．末梢型肺癌の診断率は71.1%であった．診断に関連した因子として，病変の位置，大きさ，性状，bronchus signの有無，EBUSプローブの位置，EBUS所見検出の有無，生検回数，検査時間，仮想気管支鏡ナビゲーションの使用，超音波気管支鏡ガイド下針生検併用の有無，CTスライスの厚さ，術者の医師経験年数，国立がん研究センターでの気管支鏡修練（前後）について検討した．病変の大きさ ≧ 20 mm（ 80.8% vs. 50.0%, P = 0.006），EBUSプローブの位置 “within”（90.0% vs. 50.0%, P < 0.001），EBUS所見検出あり（80.7% vs. 28.6%, P < 0.001），生検回数 ≧ 5回（78.0% vs. 47.1%, P = 0.013），気管支鏡修練後（81.6% vs. 60.5%, P = 0.043）において有意に診断率が高かった．多変量解析では，EBUSプローブの位置 “within”（ オッズ比14.10, 95%信頼区間3.53 - 56.60, P < 0.001），気管支鏡修練（オッズ比6.93, 95%信頼区間1.86 - 25.80, P = 0.004）の順に診断に寄与していた．EBUS-GSを用いた末梢型肺癌の診断率向上には，EBUSプローブの位置が病変に入っている状態（within）であること，気管支鏡修練度の向上が有用と考えられた．\nEndobronchial ultrasonography with a guide sheath (EBUS-GS) has recently been used for improved diagnostic yields for peripheral pulmonary lesions. This study retrospectively evaluated the factors related to the diagnostic yield of EBUS-GS for peripheral lung cancer. The medical records of 76 patients who had been diagnosed with lung cancer and had undergone bronchoscopy with EBUS-GS in our hospital between August 2014 and September 2015 were reviewed. The total diagnostic ratio of peripheral lung cancer was 71.1%. The following factors of the diagnostic yield were evaluated: location of pulmonary lesion; size; feature; bronchus sign; location of EBUS probe; EBUS detection; number of biopsies performed; procedure time; use of virtual bronchoscopic navigation; use of EBUS-guided transbronchial needle aspiration with EBUS-GS; CT slice thickness; operatorʼs years of medical experience; and specialized training in bronchoscopy at the National Cancer Center. In all cases, lesion size ≧ 20 mm (80.8% vs. 50.0%, P = 0.006), EBUS probe location “within” (90.0% vs. 50.0%, P < 0.001), EBUS detection (80.7% vs. 28.6%, P < 0.001), number of biopsies ≧ 5 (78.0% vs. 47.1%, P = 0.013), and bronchoscopy training (81.6% vs. 60.5%, P = 0.043) significantly contributed to an increase in the diagnostic yield. Following a multivariate analysis, EBUS probe location “within” was found to be the most significant factor affecting the diagnostic yield (odds ratio 14.10, 95% CI 3.53-56.60, P < 0.001), and bronchoscopy training was the second most significant factor (odds ratio 6.93, 95% CI 1.86-25.80, P = 0.004). EBUS probe location “within” and bronchoscopy training are the most important factors for improved diagnostic yield by bronchoscopy with EBUS-GS for peripheral lung cancer.  ","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"産業医科大学（産業医科大学学会）"}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Journal of UOEH"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.uoeh-u.ac.jp/kouza/journal/intro_e.html","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"産業医科大学雑誌"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.uoeh-u.ac.jp/kouza/journal/intro_j.html","subitem_relation_type_select":"URI"}}]},"item_10001_select_24":{"attribute_name":"記事区分","attribute_value_mlt":[{"subitem_select_item":"原著"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"ISSN　0387-821X(PRINT), ISSN 2187-2864(ONLINE)","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"内村 , 圭吾 "},{"creatorName":"ウチムラ, ケイゴ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2294","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"山﨑  , 啓"},{"creatorName":"ヤマサキ, ケイ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2295","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"石本 , 裕士 "},{"creatorName":"イシモト, ヒロシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2296","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"垣野内 , 祥 "},{"creatorName":"カキノウチ, ショウ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2297","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"木村 , 公紀 "},{"creatorName":"キムラ, コウキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2298","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"金谷  , 智子"},{"creatorName":"カナヤ, トモコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2299","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"松永 , 崇史 "},{"creatorName":"マツナガ, タカフミ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2300","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"川口  , 貴子"},{"creatorName":"カワグチ, タカコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2301","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"福田 , 洋子 "},{"creatorName":"フクダ, ヨウコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2302","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"阪上 , 和樹 "},{"creatorName":"サガガミ, カズキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2303","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"畑 , 亮輔 "},{"creatorName":"ハタ, リョウスケ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2304","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"井手口  , 周平"},{"creatorName":"イデグチ, シュウヘイ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2305","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高木  , 努"},{"creatorName":"タカキ, ツトム","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2306","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"白石  , 朝子"},{"creatorName":"シライシ, トモコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2307","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"赤田 , 憲太朗 "},{"creatorName":"アカタ, ケンタロウ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2308","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"花香 , 未奈子 "},{"creatorName":"ハナカ, ミナコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2309","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"西田 , 千夏 "},{"creatorName":"ニシダ, チナツ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2310","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"城戸 , 貴志 "},{"creatorName":"キド, タカシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2311","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"矢寺  , 和博"},{"creatorName":"ヤテラ, カズヒロ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2312","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"迎 , 寛 "},{"creatorName":"ムカエ, ヒロシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2313","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Uchimura, Keigo ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2314","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamasaki, Kei ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2315","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ishimoto, Hiroshi ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2316","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kakinouchi, Sho ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2317","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kimura, Koki ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2318","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kanaya, Tomoko ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2319","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Matsunaga, Takafumi ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2320","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kawaguchi, Takako ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2321","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Fukuda, Yoko ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2322","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sakagami, Kazuki ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2323","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hata, Ryosuke 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","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2330","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kido, Takashi ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2331","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yatera, Kazuhiro ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2332","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mukae, Hiroshi ","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2333","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-07-28"}],"displaytype":"detail","filename":"03-内村 ・吾.pdf","filesize":[{"value":"1.2 MB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"S00038103","url":"https://uoeh-u.repo.nii.ac.jp/record/732/files/03-内村 ・吾.pdf"},"version_id":"d4e04e74-2fe9-46e6-914b-817da89d2bd2"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"軟性気管支鏡","subitem_subject_scheme":"Other"},{"subitem_subject":"肺癌","subitem_subject_scheme":"Other"},{"subitem_subject":"ガイドシース併用気管支腔内超音波断層法","subitem_subject_scheme":"Other"},{"subitem_subject":"仮想気管支鏡ナビゲーション","subitem_subject_scheme":"Other"},{"subitem_subject":"末梢肺病変","subitem_subject_scheme":"Other"},{"subitem_subject":"flexible bronchoscope","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"lung cancer","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"endobronchial ultrasonography with a guide sheath","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"virtual bronchoscopic navigation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"peripheral pulmonary lesion","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ガイドシース併用気管支腔内超音波断層法を用いた気管支鏡による末梢型肺癌の診断関連因子の検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ガイドシース併用気管支腔内超音波断層法を用いた気管支鏡による末梢型肺癌の診断関連因子の検討"},{"subitem_title":"Factors Associated with Diagnostic Yield of Endobronchial Ultrasonography with a Guide Sheath for Peripheral Lung Cancer","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"4","path":["33"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-08-03"},"publish_date":"2020-08-03","publish_status":"0","recid":"732","relation_version_is_last":true,"title":["ガイドシース併用気管支腔内超音波断層法を用いた気管支鏡による末梢型肺癌の診断関連因子の検討"],"weko_creator_id":"4","weko_shared_id":-1},"updated":"2023-06-20T15:59:03.851745+00:00"}